propofol mcg/kg/min to ml/hr

endobj 0000152834 00000 n endobj 0000105730 00000 n The intersection yields your tube feed rate and the number of grams of protein that needed to be supplemented. On the left, find your patient's gender and height. Plug in the information into the formula: 10 mcg/min x 250 ml x 60 min = 3 ml/hr. For an average-size (70kg) patient, 40 mcg/kg/min propofol will provide 16.8 ml/hr propofol, which equals 443 kCal/day. >> 30 0 obj 0000000015 00000 n Therefore, the ideal approach here might be to add another agent (e.g. The goal of the tube feed cheat sheet is to make it insanely easy to create an adequate tube feed regimen. 0000151411 00000 n 10 ml/HR B. Subscribe to newsletters for the latest medication news, alerts, new drug approvals and more. 0000080527 00000 n Induction 1-2.5 mg/kg. Concentration of propofol in infusion solution: 1 gm/100 ml = 1,000,000 mcg/100 ml = 10,000 mcg/ml. 0000079809 00000 n CPB cardiopulmonary bypass. 0000080687 00000 n 0000105642 00000 n >> The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Propofol clearance ranges from 23 to 50 mL/kg/min (1.6 to 3.4 L/min in 70 kg adults). When you're done listening to the podcast. Would love your thoughts, please comment. The patient weighs 168 pounds. %%EOF Available for Android and iOS devices. Low-dose propofol infusions (e.g. 0000082104 00000 n endobj For nearly all patients, it doesn't really matter which one you use. endobj 0000103418 00000 n x��[Ys�Ƶ~��C�U;0��ue:��ȉc1�[%�R=@s�# =�Bj��s��2�t�n�J}NOo�>�wN7������_ݕ�Qv ��!��\wEsu�#�z���������U_���4��,��R��w�����ϭ=�'[�l�(ڼk���؆��lm��3��o��� ��k,K�M9T=7�WmiT!�����3w�����f7.& This site represents our opinions only. 19 0 obj %PDF-1.4 We are the EMCrit Project, a team of independent medical bloggers and podcasters joined together by our common love of cutting-edge care, iconoclastic ramblings, and FOAM. Patient Weight mcg/kg/ min 35 kg 40 kg 45 kg 50 kg 55 kg 60 kg /Type /Page provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 5 mcg/kg/min x 95 kg x 250 ml x 60 min = 36 ml/hr. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 0000151946 00000 n 0000081286 00000 n <>stream 0000081616 00000 n If this is difficult,  then it will end up on some resident's to-do list, possibly to be completed 4-6 hours after rounds. 0000096979 00000 n PROPOFOL 10 MG/ML EMULSION FOR INJECTION/INFUSION, We comply with the HONcode standard for trustworthy health information -. ] 0000103014 00000 n If using a 1 kCal/ml formula:  reduce rate by 1 x (propofol infusion rate in ml/hr), If using a 1.5 kCal/ml formula:  reduce rate by 0.7 x (propofol infusion rate in ml/hr), If using a 2 kCal/ml formula:  reduce rate by 0.5 x (propofol infusion rate in ml/hr), Add back additional protein to achieve your protein target. The infusion is mixed propofol 250 mg in 250 ml D5W. Follow. 20 0 obj 0000081369 00000 n How many ml/hr will the nurse administer? 0000096160 00000 n /Thumb 64 0 R ���d���u)�9[�g��ꬺ[��#~�RV�A�[%Ӹ���Ш����W�*�Z��{Q��q��'��u����[���t�-��YU����R5%t�~0���Ò��f�s���)w����>��O��k�Ⱦۧ����h[U��cWD�߆����y��TW���(E�s�.�2ۛFw���qk��=6�ʢ24œ��[۝L�*i���O�-og�3�������j�Ci�I��U!J��(D���n��m{����G�l�N��6���Z�u�Yw�Y�B׺Wۯ���V��������3 ��iL�,��nU�sa�n�-��S��l <> 0000152711 00000 n <> <> Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. weight kg : sedation: to: mL/hr: induction : to: mL : maintenance: to: mL/hr: Recommended IV Dosages* Sedation 25-100 mcg/kg/min. 0000084134 00000 n 0000145882 00000 n 0000080107 00000 n 0000102410 00000 n (In actual practice, we'd probably round this off to 400 mcg.min.) The conventional doses of propofol when used alone for induction and maintenance of sedation for pediatric MRI are 2-6 mg/kg and 100-250 mcg/kg/min, respectively. %���� To do this, ignore the first two columns on the left. In order to achieve this, a second high-protein cheat sheet must be used which has been modified to provide more protein (2.25 g/kg ideal body weight; see below). Propofol infusion is expected to continue for at least a day. 0000081452 00000 n endobj EMCrit is a trademark of Metasin LLC. It is chiefly eliminated by hepatic conjugation to inactive metabolites which are excreted by the kidney. (mL/hr) 60 60 60 50 280 200 120 200 160 100 75 80 Epinephrine (mcg/kg/min) — — — — 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 0.06 a 100 mL of 8.4% sodium bicarbonate given intravenously. 27 0 obj 50,000 mcg. 0000081534 00000 n 0000152465 00000 n <> In most cases, you can feed the patient based on their ideal body weight, with a target goal of 25 kCal/kg and 1.5 grams/kg protein for full nutritional support. For a patient who is significantly underweight, you want to feed them based on their actual dry weight (not their ideal body weight). 29 0 obj 0000146301 00000 n Rates of 5 to 50 mcg/kg/min or higher may be required. This can be done as shown below. 0000081699 00000 n /Parent 51 0 R That's all! 28 0 obj 0000105519 00000 n 0000152096 00000 n 0000152588 00000 n 0000079113 00000 n The infusion may be supplemented by bolus administration of 10 – 20 mg propofol (1 – 2 ml Propofol 10 mg/ ml) if a rapid increase of the depth of sedation is required. 0000086889 00000 n 19 51 �Jk��R-W��T�%ӹ2(�m[����y|�~��U�$C��d3�Fa޷��N�+�:�8}��!�bP��0�q�i�K�4p�9��d��!�ĸ�l��Qm}�=(.�ѐ�N�:�lLg�5���H( w��vpR� �~}@�+[���4-�?���p/�4�ו8In����o����So��`G߲0țuKC��b���y�>��r(�a-["�jS��m����L�n1Os��HB�. Online Medical Education on Emergency Department (ED) Critical Care, Trauma, and Resuscitation, November 1, 2016 by Josh Farkas Leave a Comment. xref 0 This question is part of Drug Dosage Calculations NCLEX Quiz 6. Propofol contains 1.1 kCal per ml. It's probably not a great idea to run propofol at rates >40 mcg/kg/min for long periods of time anyway (this will tend to cause hypertriglyceridemia). /Font <> Copyright 2009-. Propofol infusion to the desired level of sedation. 0000152039 00000 n endobj /F 23 0 R <> Dose of propofol: 5 mcg/kg/min x 80.3 kg = 401.5 mcg/min. For example, if we were determining a regimen for an underweight patient with an actual weight of 58 kg, it could be done like this: Recent guidelines recommend that morbidly obese patients should receive mildly hypo-caloric feeding with increased levels of protein. Worse yet, the team might wait for a nutrition consultation, delaying nutrition by a day. 24 0 obj endobj [ 22 0 R 0000087681 00000 n up to ~30 mcg/kg/min) won't make a big difference, but at higher doses failure to account for propofol calories could cause overfeeding. <> 22 0 obj 0000102338 00000 n 0000086807 00000 n Patient feeds are currently running at or close to the goal rate. /PageMode /UseOutlines 21 0 obj <> The cheat sheet allows this to be done in seconds, for example during rounds without missing a beat. [5,6,7] Deep sedation with high doses of propofol can predispose children to airway obstruction, respiratory depression, hypotension and bradycardia; low doses may cause patient movement necessitating the scan to be repeated. endobj endobj >> PDF options:  View Fullscreen   Download PDF. 0000102963 00000 n /Outlines 68 0 R e2 CASE REPORT ILYAS ET AL Ann Thorac Surg PROPOFOL INFUSION SYNDROME IN ADULT CARDIAC SURGERY 2009;87:e1–3 Answer … Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. atypical antipsychotic) in order to wean down the propofol dose. 25 0 obj 0000152990 00000 n >> trailer 200,000 mcg. 0000152342 00000 n /ExtGState <> For an average-size (70kg) patient, 40 mcg/kg/min propofol will provide 16.8 ml/hr propofol, which equals 443 kCal/day. On the right, select the tube feed that you are using and your nutritional target (50% or 100% calories). <> Instead, start with the third column and find the row corresponding to your patient's actual weight. Share. Example: Administer Nitroglycerin 10 mcg/min. 0000084097 00000 n No calculations are needed. Available is Nitroglycerin 50 mg in 250 ml NS. ��ws��� �?^��L�����ed*�����=ވ����}��n��}�g7���0�?/m��k�G��7����e#B�[��b�6����r/����.��X���.��x�uBv���\S�؞ �9N��8^n)+r��Vg�� @ f6B��^Ld�3�Ơ�)���ǩ�!8��\{y�����{c�$I�]�7��;љ�U.w�Y@(A?�*e]r�3�H��-T)�g�h�#��$q|i�J>�b� >� &i1�+Z�>_��߿��G�e��*"YJ8 U-3`�sH��b��&I��Y�vk+T� �Ԥ�@�hs8����\~B���[��QIG��H��V���g���i���kv���( Q[���TW��g Increase rate at 5 -10 minute intervals in increments of 5 to 10 mcg/kg/min unti l desired level of sedation is achieved. A. Clean copies of the two different cheat sheets: Nutritional support & hypocaloric tube feeding. ��F9mZ��C��f>��c��� ��ox4$��=G7˓�ᐍ��-���nmF8:XV�×з�Ѐ�h,�T���%-T߷f?��b_+=��MX��4}��a�?,���f!gF�&-��� W�����^��d��t��-i\5��#�XV����ޮ����$ X*.`����*E$`�Δ�7�JK�>k���0(T+S���Q�] @SSЩ#g�8����)If��}��3����k�����)l�����xX*)���韆�5/��P��U��Q����茎 See. Administration: For sedation: Initial infusion, (mix 1gm Propofol in 100 ml NS), 5 mcg/kg/min for 5 minutes. Patient weighs 40 kg. endobj Probably the most important aspects of nutritional care in the ICU are (1) early initiation of enteral nutrition and (2) providing adequate protein.

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